The Thyroid Hormone Regulation Pathway and Its Clinical Role in Hypothyroidism
Detailed Overview for Healthcare Professionals The regulation of thyroid hormones is governed by the hypothalamic-pituitary-thyroid (HPT) axis, a key system for maintaining metabolic equilibrium across all major body systems. The hormones Thyroxine (T4) and Triiodothyronine (T3), synthesized and released by the thyroid, play essential roles in cellular function and energy metabolism. A deficiency of these